CD274 and cancer: They found that LKB1 mutant cancer cells, in addition to having decreased PDL1 levels, showed an upregulation of pro-inflammatory cytokines as chemokine (C-X-C motif) ligand 7 (CXCL7), granulocyte colony-stimulating factor (G-CSF) and interleukin 6 (IL-6), that drive the accumulation of neutrophils and the inhibition of cytotoxic function of T cells.