DSG3 and acquired polycythemia vera: Establishing a retroviral transduction system, Takahashi et al., generated a C57BL/6J-Tg (Dsg3TCR140) mouse line which enabled them to show that while tolerized Dsg3H1 T cells could induce interface dermatitis, but not PV, non-tolerized Dsg3H1 T cells induced both anti-Dsg3 IgG production and interface dermatitis.