S100A9 and Granuloma: Granulomas from adult cattle showed more MAC387 (MΦs/monocytes), WC1 (γδ T cells), CD79+ (B lymphocytes) cells, and fewer CD3+ (T lymphocytes) cells compared to granulomas from calves In addition, we evaluated the differences between stages of granulomas, and we observed the same pattern (Figure 3; Supplementary Figure 3).