MAP2K1 and gastric cancer: CircDLST has been shown to activate the neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS)/MEK1/Ras-dependent extracellular signal-regulated kinase 1/2 (ERK 1/2) signaling pathway, acting as a miR-502–3p sponge in GC cells (Zhang et al., 2019b).