The PMAA swellsunder physiological pH conditions but collapses under the acidic pHconditions that occur under bacterial infection, allowing the releaseof AMPs.133 This novel technology exhibitedexcellent activity against MRSA, E. coli, and P. aeruginosa, thus representing a novelstimuli-responsive drug delivery technology against drug-resistantBJIs.133. The gene discussed is ADSL; the disease is bacterial infectious disease.