Race has also been found to be a risk factor for cognitive impairment in older adults; the APOE genotype has been found to be associated with cognitive impairment, and given the variations in APOE genotypes by race, especially between individuals of European and African ancestry, race plays an important role in this association and thus leads to the probability of cognitive impairment differing between races (Kim et al., 2017). The gene discussed is APOE; the disease is Cognitive impairment.