With a corrected diagnosis of anti-LGI1-encephalitis, the boy was treated with intravenous immunoglobulin with a total dose of 2 g/kg over 4 days and intravenous methylprednisolone with a regimen of 15 mg/kg/d for 3 days with a four-day interval and 3 consecutive rounds in total. The gene discussed is LGI1; the disease is viral encephalitis.