CD274 and neoplasm: Specifically, EBV miRNAs BART11 and BART173p could inhibit FOXP1 and PBRM1, respectively, thereby enhancing the transcription of PD-L1 that is crucial for tumor immune escape.207 Additionally, EBV infection could inhibit the antitumor function of NK cells infiltrated in the EBV-associated epithelial malignancies, and thus promoting the cancer development.208