In the tumor-bearing mice, the serum biochemical indicators, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine kinase MB (CK-MB), glucose (GLU), and urea also maintained unchanged except the slightly but significantly low levels of creatinine after Fe(hino)3 treatment (Additional file 1: Fig. S7D). Here, GPT is linked to neoplasm.