TP53 and neoplasm: It was classified as a cortical neoplasm with a favorable prognosis on the basis of (immuno)histological characteristics (Wieneke criteria, score: 0): tumor weight < 200 g, no capsular invasion or tumor necrosis, mitotic activity < 15/20 high-power field (HPF), Ki67 index < 15% (Fig. 2F), and strong and diffuse P53 expression (3 + intensity, 100% of positive cells) (Fig. 2G).