In this particular PCa PDX mouse model obtained from Black and White patients, we observed lower expressions of EGFR, HER2, and VEGFR after IHC staining tumor of 4NSG-SLNBT and 4NSG-SLNWT treated groups suggesting that 4NSG-SLN may not effectively suppress the expression of these receptors, however; they may be targeted for drug delivery [63, 64],. This evidence concerns the gene EGFR and posterior cortical atrophy.