For example, as components of SGs, ATX1, hnRNPA1, TDP-43, TIA1, and TAF15 can lead to the occurrence of neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD) [63, 64]. Here, HNRNPA1 is linked to Alzheimer disease.