According to Gao et al. [11] the long noncoding RNA (lncRNA) MEG3 may play a role in tumor suppression in RB, and the activation of Lnc00152 by Sp1 induces EMT through the miR-30d/SOX9/ZEB2 pathway and enhances the invasion and metastasis of RB cells through this pathway. The gene discussed is MEG3; the disease is retinoblastoma.