To determine whether the presence of relatively high numbers of proliferating and activating CD8 and CD4 T cells has an effect on the progression of KP2-OXPARPi tumors, we depleted CD4 and CD8 T cells using CD4 and CD8 depleting antibodies to KP2-OXPARPi tumor-bearing mice. The gene discussed is CD4; the disease is neoplasm.