miRNA-143-5p has been implicated in the pathophysiology of cancer (including colon and pancreatic cancers) and schizophrenia-related disorders [42, 43], and its effects on various target genes, such as EMC2, VWC2L, THY1, SGCZ, HIF1, and JDP2, among others, have been described. The gene discussed is EMC2; the disease is familial pancreatic carcinoma.