One of the main forms of non-syndromic hearing impairment is autosomal recessive deafness 1A (DFNB1A), which is caused by mutations in GJB2, including missense, nonsense, frameshift, insertion, and deletion mutations [5], and such mutations are especially common in the US, many European countries, Israel, Australia, and several Asian countries [5–9]. Here, GJB2 is linked to autosomal recessive nonsyndromic hearing loss 1A.