ANGPT1 and melanoma: Tumor vascular inhibitors are popular in the development of anti-tumor drugs at present, such as popular targets vascular endothelial growth factor (VEGF) or vascular endothelial growth factor receptor (VEGFR) family, platelet-derived growth factor (PDGF), angiopoietin 1/2 (Ang1/2), hepatocyte growth factor (HGF), galectin-3, etc. For example, molecularly imprinted polymer nanoparticles (nanoMIPs) with anti-VEGF antibodies were proved to specifically target VEGF and home to tumor mass in xenotransplantation of human malignant melanoma cells in zebrafish embryos [124].