ADL is a fully human anti-TNF mAb IgG1 approved for ankylosing spondylitis (AS), Crohn’s Disease (CD), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PsA), psoriasis (Ps), rheumatoid arthritis (RA), and urticarial vasculitis (UV). The gene discussed is TNF; the disease is Crohn disease.