Some pesticides, including DDT, dichloro-diphenyl-dichloroethylene (DDE), aldrin, and lindane, have been linked in pre- and post-menopausal women to a higher risk of BC [49,50], either estrogen receptor-positive (-hexachlorocyclohexane and Pentachlorothioanisole) [51] or HER2-positive tumors (DDT) [52,53,54]. The gene discussed is ESR1; the disease is breast cancer.