IGHE and allergic bronchopulmonary aspergillosis: One study found that IgE from patients with allergic bronchopulmonary aspergillosis (ABPA) can recognize human thioredoxin as an autoantigen, suggesting amino acids shared between human and fungal thioredoxin are involved in IgE binding and confirming that IgE-mediated cross-reactivity and autoreactivity are involved in chronic atopic disease by molecular mimicry [79].