The immunohistochemical KLK12 status was positively associated with ER status (p = 0.036) and PR status (p = 0.0058), while it was inversely associated with the stage (p = 0.0007), pathological T factor (pT) (p = 0.0002), lymph node metastasis (p = 0.030) and distant metastasis (p = 0.035). The gene discussed is PGR; the disease is metastatic malignant neoplasm in the lymph nodes.