ESR1 and breast cancer: Similar tendencies were detected in both ER-positive cases (p = 0.0047 for metastasis-free survival (Figure 3C) and p = 0.16 for breast cancer-specific survival) and ER-negative cases (p = 0.086 for metastasis-free survival (Figure 3D) and p value was not evaluated for breast cancer-specific survival because no patient died in KLK12-positive group).