We examined the impact of MGN and MGO complex by analyzing the mass of tumors, the activity of caspase 3 (CASP3) and caspase 8 (CASP8), the expression of pro-inflammatory proteins at the protein level, and the levels of malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione (GHS). The gene discussed is CASP8; the disease is idiopathic membranous glomerulonephritis.