Our results also make a strong case of a role for enteroviruses in T1DM etiology but suggest that the main target of enterovirus antibodies is not INS (as most previous research has attempted to demonstrate) but rather INSR, a T1DM target other investigators have previously reported [4,5,6,7,8,9,54,82,83,84,85,86]. This evidence concerns the gene INSR and type 1 diabetes mellitus.