INSR and type 1 diabetes mellitus: Figure 12 provides the peptide sequences and their similarities to either INS or INSR. Clostridium similarities to the INS A chain were specifically chosen because the role of the A chain in the induction of T1DM is generally ignored in favor of the B chain. Figure 12 also demonstrates that a COX peptide mimicking INSR does bind to both Clostridium (INS A chain mimic) peptides.