In particular, the combination of the rs1544410 (BsmI) C, rs7975232 (ApaI) C, and rs731236 (TaqI) A alleles in the NR1I1 CCA (bAt) haplotype was significantly associated with the progression of fibrosis and the development of cirrhosis and HCC in HCV-infected patients who were diagnosed with alcohol-induced liver injury [37,38,39]. The gene discussed is VDR; the disease is hepatocellular carcinoma.