SCN1B and Brugada syndrome: Five (potentially) pathogenic, SCN10A variants: c.472T > G, c.2441G > A and c.5657C > T, SCN1B variant c.457G > A, and SCN3B variant c.583G > A, have not been seen in patients with painful-DPN and SFN, but three of them have been tested functionally and reported as disease-causing for atrial fibrillation [22], and three VUSs have been reported in patients with Brugada syndrome, atrial fibrillation, and long QT syndrome [27,28].