The detection of the overexpression of miRNAs involved in angiogenesis or those that are suppressed or underexpressed for the same reason in combination with tumor markers (e.g., TGF-β, VEGF, CEA or CA15-3) could anticipate a diagnosis before tumor dissemination is produced, helping the treatment response and a reduction in sequels. The gene discussed is VEGFA; the disease is neoplasm.