Therefore, we can conclude an association between DRP2–4E-BP2–eIF4E in the vulnerable CA1 region after ischemia reperfusion that would reduce the availability of “active” eIF4E (unbound to 4E-BP2), essential to protein synthesis, an association that would be dependent on DRP2 phosphorylation. This evidence concerns the gene EIF4EBP2 and ischemia.