In addition, the expression of paxillin in esophageal squamous cell carcinoma was confirmed by immunohistochemistry to be higher than that in adjacent non-tumor cells, but no correlation was found between the expression of paxillin and the overall survival rate of patients, and paxillin was not an effective prognostic marker for patients [47]. The gene discussed is PXN; the disease is esophageal squamous cell carcinoma.