Several chromosomal loci (1p13.2–1q22, 2q21, 14q32, 19p13.2, and 8p23.1–p22) [16,17,18,19] and low-penetrance mutations in NKX2.1, FOXE1, HABP2, RTFC, MYH9, and CHEK2 have been identified to confer susceptibility to non-syndromic FNMTC [20,21,22,23,24,25]. Here, FOXE1 is linked to familial papillary or follicular thyroid carcinoma.