PIK3CA and familial papillary or follicular thyroid carcinoma: We identified two variations in genes in which germline variations cause susceptibility to FNMTC (Supplementary Table S1) and in 13 somatic genes with genetic alterations in malignant thyroid nodules (NRAS, HRAS, KRAS, THADA, PIK3CA, BRAF, TERT, PAX/PPARG, PTEN, DICER, E1F1AX, TSHR, and TP53) [57].