Ferrante et al. reported that the expression levels of Th1-related cytokines, such as TNF-α, IFN-γ, IL-12, and IL-27, were upregulated at the mRNA level in 11 patients with intestinal BD compared with healthy controls, which could inhibit the differentiation of Th0 cells into Th17 cells [30]. Here, IFNG is linked to Behcet disease.