MAP3K7 and hepatocellular carcinoma: Another study in hepatocellular carcinoma (HCC) showed that the transfer of miRNA to the parental cells via exosomes contributed to multifocal tumor growth by decreasing the expression of transforming growth factor beta-activated kinase-1 (TAK1) [20,21], establishing it as a potentially critical target candidate for regulation via exosomal miRNA [22].