Notably, Van Limpt, V.A., et al. [69] analyzed the expression of 21 genes involved in the NOTCH pathway in a large panel of NB cell lines, and the gene expression appeared to be the highest in the non-MYCN-amplified cell lines, such as SK-N-FI, LAN-6, SHEP, and LAN-2 [69]. The gene discussed is MYCN; the disease is neuroblastoma.