LGALS3 and breast carcinoma: For example, Gal3 is highly expressed in the colon, head and neck, liver, gastric, endometrial, thyroid, skin, and breast carcinomas [55,56,66,88,89,90], while decreased expression of Gal3 is observed in the prostate [67,91], bladder [92], kidney [93], and pituitary cancers [94].