RAPGEF6 and neoplasm: Using TSVdb, a web tool allowing for the comparison of isoform expression among clinical subgroups (http://tsvdb.com/index.html accessed on 19 April 2023) [89], we found that RapGEF6 exon 21A is upregulated in TCGA-STAD tumor samples compared with normal ones (Figure 5B and Table S6).