PTPRZ1 and colorectal carcinoma: By analyzing the mRNA levels of PTPRZ1 in 16 tissues obtained from patients with colorectal carcinoma, no significant difference in the Ptprz1 gene expression was found compared to the corresponding normal tissues [93]; similarly, the protein PTPRZ1 levels were not found to be different between 25 colorectal carcinoma and 5 normal tissues, studied by immunohistochemistry and Western blot analysis [94].