The expression of NGF and BDNF has been also largely described in ocular tissues and in tears of patients with ocular pathologies [8,9], but no studies have investigated the profile of NGF and BDNF and their precursors in serum and tears in correlation with ophthalmological and or no ophthalmological manifestations and symptoms of Graves’ disease (GD). The gene discussed is BDNF; the disease is Graves disease.