The role of the CCR5-CCL5 axis in CTCL is not completely understood, and CCR5 expression may be limited to a rarer type of CTCL, namely, subcutaneous panniculitis-like T-cell lymphoma [34,35], so further studies are needed to determine how these changes may affect CTCL pathogenesis. The gene discussed is CCR5; the disease is primary cutaneous T-cell non-Hodgkin lymphoma.