In contrast, the following PAI-1 alleles were associated with decreased stroke risk: ‘AA/TT’ (rs2227631/rs11178), ‘4G4G/GA’ (rs1799889/rs6092), ‘GA/TT’ (rs6092/rs11178), ‘GA/GG’ (rs6092/rs7242), and ‘GA/GG’ (rs6092/rs1050955). Here, SERPINE1 is linked to Stroke.