Confirming our protein and qPCR findings, the 24 h stimulation with IL-27 also strongly increased the expression of both PD-L2 (PDCD1LG2) and IDO1 in mDCs from HCs (z-score 13, p = 0.006 and z-score 6.6, p = 0.009, respectively), while these genes only showed a non-significant trend to increase in the mDCs of patients with MS (Supplemental Figure S4). Here, IL27 is linked to myeloid sarcoma.