IL1B and myeloid sarcoma: The IL-1β involvement in MS was studied by Prins et al. They observed that the presence of IL-1β and IL-1ra-expressing cells in white matter regions of the brain in their experimental MS model was consistent with increased IL-1β [44] and IL-1ra [45] expression in active white matter lesions in post-mortem brain material of MS patients and of the animal EAE model for MS.