In this regard, Laurence et al. justified the already known close association between Parkinson’s disease and seborrheic dermatitis by attributing a not negligible pathogenic role to T cell compartment immunosenescence, particularly involving the weakened control action of immunosenescent CD4+T cells on Malassezia overproliferation, both at skin and central nervous system sites [180]. Here, CD4 is linked to seborrheic dermatitis.