Comparing CTRL and ischemic stroke samples, higher levels of the soluble Intercellular Adhesion Molecule 1 (ICAM-1, also known as CD54; Figure 2A), as well as IL-6 (Figure 2B), IL-10 (Figure 2C), TNFα (Figure 2D) and Leptin (Figure 2E) were observed, even though only ICAM-1, IL-6, IL-10 and TNFα proved to be significantly increased in the serum of stroke patients compared to CTRL (p < 0.001, Mann–Whitney test). The gene discussed is LEP; the disease is ischemic stroke.