Quantification of the ORO-positive area demonstrated a statistically significant reduction (p < 0.0001) in lipid-filled lesions formed in the aortic sinus of smOGTKOApoE-/- mice vs. smOGTWTApoE-/- with intact OGT, in response to Western diet-induced hyperglycemia (Figure 6C). Here, OGT is linked to Hyperglycemia.