APOB and metabolic syndrome: Metabolic syndrome is characterized by abdominal obesity, high blood pressure, insulin resistance (a risk factor for T2DM), a proinflammatory and prothrombotic state, and atherogenic dyslipidemia (high triglycerides, high apolipoprotein B, high low-density lipoprotein particle (LDL-p) number, and low high-density lipoprotein cholesterol (HDL-C) [3,5,13,14].