HTR2A and disorder of sexual differentiation: Previous studies using SCI rat models showed that inefficient voiding and DSD evident as tonic EUS activity during voiding bladder contractions were improved by systemic or intrathecal activation of 5-HT receptors such as 5-HT2A/2C, 5-HT7 or 5-HT1A, and that the expression of 5-HT2A/2C and 5-HT7 receptors were upregulated in lumbosacral cord motoneurons in the Onuf’s nucleus [86,87,88].