In a similar study, Svatek et al., using a multiplex, particle-based PRISMA cytometric assay to detect MMP-1, 2, 3, 7, 8, 9, and 12 in a U.S. cohort of patients with invasive UBC, found that elevated preoperative plasma MMP-7 levels were associated with significantly shorter time to cancer-related mortality [21]. Here, MMP1 is linked to cancer.