As miR-302a-3p directly targets SOCS5 to boost STAT3 phosphorylation and induce the transcription of STAT3 target genes, SMARCA2 starts the miR-302a-3p/SOCS5/STAT3 signaling axis and thus potentiates pancreatic cancer metastasis [207]. This evidence concerns the gene STAT3 and familial pancreatic carcinoma.