The literature and database review showed that these three genes could also be related to the development of cancer, either by playing an indispensable role in the activation of the MAPK pathway (in the case of DNAH11) [50] or, as immune cytokines, in the case of CCDC134 and IL16, affecting the signaling activity that facilitates tumor progression [51,52]. The gene discussed is IL16; the disease is neoplasm.