NKD1 and thyroid gland carcinoma: In this family, in addition to the strong candidate variant in NKD1 and the pathogenic mutation in a functional domain of the TC-gene TG [75], we also found four variants in the genes ROBO1, MYH10, CSMD2 and STK32A, all of them with a positive expression in thyroid cancer according to public databases, suggesting that they could play a role in familial NMTC development.