Furthermore, alternariol (AOH), which is another sphinganine analog mycotoxin, was found to be responsible for strong oxidative stress by generating ROS, causing lipid peroxidation, and increasing SOD activity at 3.125 to 100 μM after a 24, 48, and 72 h treatment in human colon adenocarcinoma (Caco-2) cells [55]. The gene discussed is SOD1; the disease is colon adenocarcinoma.