In the men’s group the inter-SNP interactions of eight loci in only seven models have been registered as HTN-involved (pperm ≤ 0.022, polymorphic loci of two genes—ARHGAP42 rs633185 C > G, ATP2B1 rs2681472 A > G, not included in these models) (Table 3). The gene discussed is ATP2B1; the disease is hypertensive disorder.