Three genes/polymorphisms such as RGL3 rs167479 T > G (it is included in 18 models), TBX2 rs8068318 T > C (16 models), HFE rs1799945 C > G (13 models) make the prevailing contribution to HTN susceptibility (they were part of 50% of models and more). This evidence concerns the gene HFE and hypertensive disorder.